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Multiple Endocrine Neoplasia, Type 1 [MEN 1]

Some diseases rarely occur in the human body. One such disease is known as multiple endocrine neoplasias, type 1 or MEN 1. It is a disorder of the endocrine glands that affect hormone production.

About Multiple Endocrine Neoplasia, Type 1 

Multiple endocrine neoplasia, type 1, is a rare disease which causes tumors in the endocrine glands and parts of small intestine and stomach

The endocrine glands exist in various parts of the body. The function of these glands is to produce hormones relating to sexuality, digestion, and growth. 

In  MEN 1, tumors occur in the endocrine glands, stomach, and small intestines in multiple locations . Moreover, they cause overproduction of hormones which may become problematic. 

The tumours are likely to be benign . This condition is quite rare and inherited and affects only one(1) person out of 30,000.

What are the Symptoms of Multiple Endocrine Neoplasia, Type 1?

The symptoms of multiple endocrine neoplasia, type 1 , happen due to the overproduction of hormones by the tumors . Below are the wide variety of symptoms of multiple endocrine neoplasia, type 1.

  • Kidney stones
  • Constipation
  • Frequent diarrhea
  • Depression
  • Excessive thirst 
  • Digestive problems 
  • Low blood glucose
  • Muscle weakness
  • Enlarged/swollen hands and feet
  • Tiredness
  • Excessive urination
  • Aches and pains in joints/bones
  • Stomach ulcers
  • Acid reflux
  • Abdominal pain

What are the Causes of Multiple Endocrine Neoplasia, Type 1 ?

Multiple endocrine neoplasia, type 1, is an inherited or genetic disorder. The most important cause of this disorder is the mutation in the gene known as MEN1. 

When to See a Doctor?

You should see the doctor when you begin to experience multiple symptoms of this disorder. Its symptoms can easily be confused for other problems. But, if you have a family history of this disorder, you must  seek medical  advice  immediately. 

Apollo Hospitals have specialists that can effectively treat MEN 1.

Request an appointment at Apollo Hospitals. 

Call 011 4004 3300 to book an appointment.

How Can You Prevent Multiple Endocrine Neoplasia, Type 1?

Since multiple endocrine neoplasia, type 1 , is an inherited disorder, there is not much you can do to prevent it. Nevertheless, several tests are available to detect this disease and manage it before it becomes severe. 

Below are the various tests for those with a family history of multiple endocrine neoplasia, type 1.

Genetic Testing: You should undertake genetic testing if your family has been diagnosed with multiple endocrine neoplasia, type 1 .

MRI or computed tomography: A scan every 2 to 4 years of the abdomen region and chest region. MRI must commence at the age of 20.

Blood Testing: Blood tests as advised by the doctor should take place regularly. 

What are the Treatment Multiple Endocrine Neoplasia, Type 1?

Below are the two main treatment options for multiple endocrine neoplasia, type 1 :

  • Surgery: Here, surgical removal of the tumors of multiple endocrine neoplasia, type 1 MEN 1, takes place.
  • Medication: Certain medications can suppress the functioning or further growth of the tumors of multiple endocrine neoplasia, type 1 .

Conclusion

Multiple endocrine neoplasia, type 1, is a genetically acquired disorder. If you are one of those diagnosed with it, there is no reason to lose heart. The treatment options for it are available and have become effective over the years. 

Frequently Asked Questions (FAQs)

How likely is my child to acquire multiple endocrine neoplasia, type 1 from me?

Since multiple endocrine neoplasia, type 1, is an inherited disorder, your child can inherit it from you. Children have a 50% chance of inheriting multiple endocrine neoplasia, type 1 from their parents. So, screen your child early .

Is multiple endocrine neoplasia, type 1 MEN 1 life-threatening?

Usually, multiple endocrine neoplasia, type 1 , is not life-threatening. However, it can have adverse effects on the body due to its wide range of symptoms. 

 Are the tumors of multiple endocrine neoplasia, type 1 MEN 1 cancerous?

No, the tumors of multiple endocrine neoplasia, type 1, are usually non-cancerous or benign.

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